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Author

Shuo Wan

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Aug 2026

Systematic Metabolic Engineering of Escherichia coli for High-Level Production of trans-4-Hydroxy-L-proline.

As a high-value-added amino acid derivative, trans-4-hydroxy-L-proline (T-4-Hyp) faces key bottlenecks in its microbial production from glucose, including insufficient precursor supply and an imbalance between cell growth and product biosynthesis. In this study, we successfully constructed an engineered Escherichia col...

Kai Wang, Shu-Ping Tian, Shuo Wan et al. · 0 citations

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