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Author

Shyam A. Patel

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Open access Oct 2026

Contemporary Clinical Outcomes and Healthcare Utilization in Older Adults with Acute Myeloid Leukemia: Insights from a Single-Center Retrospective Cohort

Simple Summary Many older adults with acute myeloid leukemia (AML) cannot receive intensive treatment because of comorbidities or frailty. Newer, lower-intensity treatments have expanded options for these patients. In this retrospective analysis, we examined treatment patterns, survival, and healthcare utilization in p...

Tina Y. Zhang, Alex Y. Ge, Shyam A. Patel et al. · 0 citations
Review Open access Jul 2026

Multi-antigen chimeric antigen receptor-T cell therapy for relapsed/refractory B cell lymphomas

The mechanisms underlying primary and secondary refractoriness to conventional single-targeting CAR-T therapies for B cell lymphomas are discussed and the ongoing challenges with existing CAR constructs are explored.

Toshali Pandey, D. Samat, Saurabh Dahiya et al. · 1 citation
Review Open access Aug 2026

Menin Inhibitors in Acute Myeloid Leukemia: Clinical Integration, Resistance, and the Path Beyond Monotherapy

Looking ahead, menin inhibitors may increasingly be incorporated into earlier lines of therapy, used as maintenance following allogeneic stem cell transplantation, and integrated into treatment approaches guided by measurable residual disease and evolving patterns of drug resistance.

Tina Y. Zhang, Shyam A. Patel, Talha Badar · 0 citations

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