Alleviation of high-lipid diet-induced hepatic steatosis and intestinal injury by berberine in yellow catfish (Pelteobagrus fulvidraco) is associated with modulation of the intestinal microbiota and the FXR pathway.
High-lipid (HL) diets are commonly used in fish farming for their cost-saving and growth-promoting benefits, but often cause hepatic steatosis and intestinal dysfunction. Berberine (BBR), a natural plant alkaloid, exhibits lipid-lowering and health-improving properties, yet its mechanism remains unclear because of its...