Si-Min Liu

C. elegans CEH-43/DLX drives convergent astrocyte differentiation by sequential control of axon guidance and synaptic gene expression programs.

Mammalian radial glia can remodel into astrocytes, which acquire common transcriptional identities despite arising from spatially and lineally distinct progenitors. The molecular mechanisms underlying convergent radial glia-to-astrocyte transformation are not fully understood. To identify regulators of this process, we...