Review
Open access
Oct 2026
Targeting inhibitory phagocytosis checkpoints in cancer immunotherapy: mechanisms, therapeutic strategies, and translational challenges
Tumors evade macrophage-mediated clearance through mechanistically distinct but functionally convergent anti-phagocytic pathways. This review examines canonical and emerging receptor–ligand “don’t eat me” axes, Siglec-dependent glyco-inhibitory checkpoints, and an emerging noncanonical glycocalyx barrier associated wit...
Jie Li, Mei Ding, Jian Sun et al.
· Frontiers in Immunology · 0 citations