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Si-Si Chen

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Open access Oct 2026

ESR1 bridges GNGT1 to CLDN6 in promoting gastric cancer stemness and development

Gastric cancer (GC) remains a major global health burden, and the molecular determinants driving its progression are incompletely understood. In the present study, G protein subunit gamma transducin 1 (GNGT1) was identified as a clinically relevant oncogenic driver that promotes GC growth, stemness, and metastatic...

Yan Zhang, Si-Si Chen, Z. Zhuang · 0 citations

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