Author

Si-Tao Xu

3 papers indexed here

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Sep 2026

A Modular (1,3-Oxathiolan-2-yl)ethoxy Trigger Unlocks Activatable Probes for In Vivo Imaging of Hypobromous Acid

Hypobromous acid (HOBr) is a critical reactive oxygen species in inflammatory pathology; however, tracking its dynamics in vivo remains a formidable challenge. Herein, we report a convenient, sensitive and selective (1,3-oxathiolan-2-yl)ethoxy (OTE) recognition moiety for the development of activatable HOBr probes th...

Xin Jin, Tian-Bao Lu, Si-Tao Xu et al. · Analytical Chemistry · 0 citations

Open access Sep 2026

Integrated Pharmacokinetics, Pharmacodynamics, and Pharmacometabolomics to Elucidate Guizhi Fuling Capsule’s Homeostatic Mechanism Against Acute Dysmenorrhea

Background/Objectives: Guizhi Fuling Capsule (GZFL), a Traditional Chinese Medicine (TCM) formula, is widely used for primary dysmenorrhea and other blood-stasis gynecological disorders. This study aimed to characterize its material basis, elucidate its multi-component, multi-target mechanism against acute primary dysm...

Xin-Ru Lyu, Min Lin, Zi-Han Xu et al. · Pharmaceuticals · 0 citations

Open access Aug 2026

Paeonol and Its Metabolites Alleviate LPS/D-GalN-Induced Acute Liver Injury in Mice: Potential Involvement of NDUFS7 and Macrophage Mitochondrial Function

Acute liver injury (ALI) is a severe clinical syndrome characterized by systemic inflammation and mitochondrial oxidative stress. This study investigated the hepatoprotective effects of paeonol (PA) in LPS/D-GalN-induced ALI and explored the potential involvement of macrophage mitochondrial function and NDUFS7. Proteom...

Xin-Ru Lyu, Si-Tao Xu, Nai-Lun Su et al. · Antioxidants · 0 citations