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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Si-Wen Hao

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Aug 2026

A novel TK/gE-deleted pseudorabies virus vaccine expressing CCL3L1 enhances humoral immunity by stimulating the dendritic cell-T follicular helper-germinal center axis.

Results demonstrate that CCL3L1 acts as an effective molecular adjuvant by potentiating humoral immunity through activation of the conventional DC-T follicular helper cell-GC B cell axis, supporting HNX-ΔTK/ΔgE-CCL3L1 as a potential vaccine for the control of emerging PRV variants.

Lun Yao, Si-Wen Hao, Chengjun Zhang et al. · 0 citations

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