Si-Yu Yang

Integrative Multi‐Omics Profiling Reveals Age‐Associated Genomic and Tumor Microenvironmental Heterogeneity in Colorectal Cancer

Early‐onset colorectal cancer (EOCRC) is increasing worldwide, yet the molecular basis underlying its age‐related heterogeneity remains insufficiently defined. To address this gap, we performed whole‐exome sequencing in a Chinese EOCRC cohort diagnosed before 40 years of age ( n  = 111), bulk transcriptome sequen...