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Si-Yu Zhao

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Review Open access Sep 2026

The Role of Mitochondrial Dysfunction in Hepatocellular Carcinoma: From Pathogenesis and Drug Resistance to Targeted Therapeutic Strategies

Abstract Hepatocellular carcinoma (HCC) is characterized by high malignancy and widespread drug resistance at advanced stages, posing formidable challenges in clinical diagnosis and treatment. Mitochondrial dysfunction is a core driver of HCC initiation and drug resistance. However, how its plasticity dynamically regul...

Si-Yu Zhao, Qian Liu, Jing Li et al. · 0 citations

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