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Siddharth Balachandran

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Open access 2026

ZBP1-mediated sensing of genomic stress in cancer therapy

ZBP1-mediated nucleic acid surveillance represents a central innate checkpoint bridging genomic stress to antitumor immunity, and integrating epigenetic priming, nanomedicine, and patient stratification according to ZBP1/RIPK3/MLKL pathway status holds promise for overcoming therapeutic resistance.

Xiao Zhong, Siddharth Balachandran, Ting Zhang · 0 citations

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