Siham H. A. Al-Mawri

Extractive ion-pair spectrophotometric methods utilizing bromocresol green to estimate chlorpheniramine maleate in pharmaceutical formulations

Two accurate, sensitive, and cost-effective spectrophotometric methods were developed and validated for the quantitative determination of Chlorpheniramine Maleate (CPM). Method A is based on the formation of a yellow ion-pair complex between CPM and bromocresol green (BCG) in an acidic medium. The resulting complex...