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Author

Silja Mordhorst

2 papers indexed here

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Open access Sep 2026

A Biotechnological Platform for Gram-Scale Production of Mureidomycin A

Mureidomycin A is a uridyl peptide antibiotic with potent bioactivity against the Gram-negative pathogen Pseudomonas aeruginosa. Crucial bottlenecks impeding further drug development include low compound production in native producers and heterologous hosts, as well as the formation of numerous derivatives, which fur...

Panagiota-Hanna Koutsandrea, Richard Sonnengrün, Nils Hauck et al. · 0 citations
Review Open access Sep 2026

Radical SAM-dependent enzymes: Jacks-of-all-trades in RiPP pathways.

Covering: up to 2026The cofactor S-adenosyl-L-methionine (SAM) plays a key role in the biosynthesis of ribosomally synthesised and post-translationally modified peptide (RiPP) natural products. SAM-dependent enzymes have been shown to catalyse important steps in RiPP biosynthesis, including methylation, desaturation, e...

Panagiota-Hanna Koutsandrea, Lorenz Thost, Alicia Courvoisier-Clément et al. · 0 citations

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