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Author

Silvère Baron

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Review Open access Oct 2026

Three Decades of Liver X Receptor Agonist Chemistry: Structural Motifs, Structure-activity Relationship, and Therapeutic Prospects.

Liver X receptors (LXRs) are nuclear receptors that play an important role in the regulation of gene expression involved in lipid metabolism, cholesterol homeostasis and inflammation. Certain modifications in endogenous LXR activity have been associated with pathological conditions and diseases. The dysregulation of LX...

N. Delporte, Aurélie Lagarde, P. Chalard et al. · 0 citations

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