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Simon Schwoerer

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Sep 2026

Abstract A013: Tumor microenvironmental metabolites regulate cancer-associated fibroblast heterogeneity

Pancreatic ductal adenocarcinoma (PDAC) is characterized by a prominent desmoplastic response with a high abundance of cancer-associated fibroblasts (CAFs). CAFs are a functionally and transcriptionally heterogeneous population of cells and include inflammatory CAFs (iCAFs), thought to promote tumor growth via the se...

Simon Schwoerer, Chu-Fan Cai, Jessica Stradley et al. · 0 citations

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