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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Simone A. Beckham

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Open access Aug 2026

Long-read sequencing quantifies synthetic mRNA abundance, integrity and host response in vivo

Applied to lipid nanoparticle (LNP) delivered mRNA in mice, the method revealed tissue-specific delivery and degradation patterns and uncovered a critical disconnect between mRNA accumulation and protein expression across organs.

Victoria McLeod, D. Yuen, Moore Z. Chen et al. · 0 citations

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