T and B cell–mediated immunosurveillance of the central nervous system (CNS) can become maladaptive in multiple sclerosis (MS). Epstein–Barr virus (EBV) is a likely driver of MS, yet how exactly EBV-specific T cells contribute remains unclear. We generated an antigen-resolved atlas of blood and cerebrospinal fluid (CSF...
N. Kristensen, T. Tsaktanis, S. Frischholz et al.· bioRxiv· 0 citations
Classically, B and T cells are differentiated by their mutually exclusive expression of surface markers such as CD3 and CD20, but it is now established that a few percent of T cells in human blood display also CD20. We analyzed CD3+CD20+ cells in detail by combining single-cell proteogenomics, FACS, and ImageStream. Th...
Selia Baier, Zhong-Yi Wang, N. Loll et al.· Proceedings of the National...· 0 citations
MLC1 antibodies identify a subset of patients with an NMOSD-like phenotype, underscoring their potential as a disease marker with pathogenic relevance.
H. Wong, Samantha Ho, Qian Yu et al.· Science Translational Medici...· 0 citations
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