Review
Open access
Aug 2026
Advances in quinazolin-4-one scaffolds in breast cancer therapy: emerging designs, mechanistic perspectives and SAR trends (2015-2025).
This review highlights the structure-activity relationship (SAR) of different quinazolinone derivatives along with their binding interactions which indicate that the electronic and lipophilic characteristics of substituents on different positions of the quinazolinone core significantly affect their activity in breast cancer.
Simran Kaur, Shivani Kasana, B. Kurmi et al.
· RSC Medicinal Chemistry · 0 citations