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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Sinan Karageçili

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2 papers indexed here

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Open access Oct 2026

Structure-based computational prioritization of Emodin-8-glucoside as a candidate ligand for the VEGFR1 kinase domain in the context of placenta previa

Placenta previa is a serious obstetric condition associated with abnormal placental implantation and hemorrhagic complications, for which no targeted pharmacological therapy is established. This study applied an integrated structure-based computational workflow to explore the intracellular VEGFR1 kinase domain as a can...

Deniz Inan, Sinan Karageçili, Nouman Ali · 0 citations
Sep 2026

Fragment-Based AI Optimization of Tranexamic Acid Derivatives Targeting the Kringle 1 Lysine-Binding Site of Human Plasminogen: An Integrated Computational Study for Postpartum Hemorrhage

Postpartum hemorrhage remains a leading cause of maternal mortality worldwide, frequently associated with excessive fibrinolysis mediated by plasminogen activation. Tranexamic acid (TXA) is widely used as an antifibrinolytic agent; however, optimization of its scaffold may improve binding characteristics and pharmacolo...

Sinan Karageçili, Deniz Inan, Nouman Ali · 0 citations

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