Systematic characterizations of a urinary protein, prosaposin, as a novel inhibitor of calcium oxalate stone formation.
The development of calcium oxalate (CaOx) stones in the kidney comprises multiple processes involving sophisticated interactions between stone minerals and other molecules, especially urinary proteins. Prosaposin (PSAP) has recently been identified in the urine from healthy (non-stone) subjects, not in the urine from C...