Sirous Rafiei Asl

Neuroprotective potential of linagliptin against mancozeb induced neurotoxicity

The research investigates the neuroprotective effects of Linagliptin (Lina), a dipeptidyl peptidase-4, against the neurotoxic impacts of Mancozeb (MNZ), which is known to cause cognitive deficits and oxidative stress. Methods: The study involved six groups of rats, with behavioral assessments conducted through va...

Zingerone mitigates cognitive and motor impairments in a D-galactose-induced brain aging model: Role of oxidative stress and neuroinflammation

Ketotifen attenuates paraquat-induced nephrotoxicity in mice via suppression of oxidative stress and inflammation.

Background and purpose Paraquat (PQ) is a toxic herbicide to humans and animals that causes kidney damage. Ketotifen (KTF) is a first-generation antihistamine and a potent mast cell stabilizer with antioxidant and anti-inflammatory properties. This study aimed to evaluate the protective effect of KTF against PQ-induced...