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Sithara Vivek

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Open access Sep 2026

Proteomic insights into childhood adversity: Exploring biological mechanisms and cognitive outcomes in the CARDIA study

Adverse childhood experiences (ACEs), including abuse, neglect, and household dysfunction, are among the most consequential adverse social experiences of early life and carry elevated risk of chronic disease and cognitive impairment in adulthood through biological pathways that are poorly understood. We examined the me...

Deborah K. Rose, Gabrielle N. Pfund, Robin Ortiz et al. · 0 citations
Open access Sep 2026

Longitudinal associations of one-carbon metabolism biomarkers with biological and epigenetic aging in older adults in India.

Transition to folate deficiency and persistent hyperhomocysteinemia were associated with accelerated aging across Phenotypic Age and DNA methylation-based aging measures, with folate exhibiting the strongest inverse associations with DunedinPACE and SystemsAge.

Jian-Feng Wang, Eileen M. Crimmins, Jung Ki Kim et al. · 0 citations

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