Accumulating epidemiological and toxicological evidence implicates the herbicide paraquat (PQ) as an environmental risk factor for depressive neuropsychiatric disorders. In this study, we demonstrated that PQ exposure induces depression-associated neurobehavioral abnormalities in adult zebrafish. Subsequent examination...
Zhen Yu, Li-Sha Li, Chen-Hao Jin et al.· Ecotoxicology and Environmen...· 0 citations
To investigate the associations of objectively measured daytime and nighttime ambient light exposure with depressive symptoms in U.S. adults to explore whether selected liver-related biomarkers statistically accounted for part of these associations. We conducted a cross-sectional analysis of 7,556 adults from NHANES 20...
It is shown that EVs released by microglia exposed to 40 μM paraquat are internalized by dopaminergic neurons, where they impair glucose metabolism and induce neurodegenerative injury through the intercellular transfer of tenascin-C (TNC).
A pivotal role for m7G modification in environmental neurotoxicant-induced neurodegeneration is established and cobalt-related RNA regulatory paradigm is revealed that expands the understanding of heavy metal-driven epitranscriptomic dysregulation, and hence offering novel therapeutic targets.
Jianping Tang, Yanbin Ren, Jingwen Li et al.· Ecotoxicology and Environmen...· 1 citation
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