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Author

Siyu Tong

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Sep 2026

CCL2/CCR2 axis suggests a role in bridging obesity-related adipose inflammation to Sertoli cell injury in asthenozoospermia: Integrated multi-omics, machine learning and in vitro validation.

This study established an integrated framework combining multi-omics analysis, machine learning (ML), single-cell RNA sequencing (scRNA-seq), molecular docking, and in vitro validation to investigate potential mechanisms and therapeutic targets of obesity-associated asthenozoospermia (AZS). Based on transcriptomic data...

Peng-Rui Wang, Fei Teng, Siyu Tong et al. · 0 citations
Aug 2026

Endoplasmic Reticulum Stress-Related Immune Signature in Atrial Fibrillation: Machine Learning and Single-Cell Transcriptomics.

This study describes a reproducible computational workflow for identifying endoplasmic reticulum stress (ERS)-related gene signatures in atrial fibrillation (AF) by integrating bulk transcriptomics, machine learning, immune infiltration analysis, and single-cell transcriptomics. Public bulk transcriptomic datasets were...

Qing-Rui Li, Fei Teng, Xiangyu Ji et al. · 0 citations
Aug 2026

Association of MPO Expression with the Immune Microenvironment in Breast Cancer: Insights from Bioinformatics and Single-Cell Analyses.

This study provides a reproducible in silico workflow for generating hypotheses about MPO-associated immune/myeloid features in breast cancer, which require external cohort validation and experimental confirmation.

Qing-Rui Li, Fei Teng, Weijia Kong et al. · 0 citations

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