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Author

Sofia Koenig Gimeno

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Review Open access Oct 2026

ER-Nε-lysine acetylation machinery in neurological disorders: A context-dependent regulator of proteostasis.

Despite extensive characterization of cytosolic and nuclear acetylation, the functional relevance of luminal ER-Nε-lysine acetylation in the nervous system remains poorly understood. This modification is mediated by a coordinated metabolic-secretory axis involving acetyl-CoA availability and the ER-resident acetyltrans...

Emanuele Di Martino, R. A. de Vos, Sofia Koenig Gimeno et al. · 0 citations

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