Miltefosine regulates gene expression related to morphogenesis and zinc metabolism in Candida albicans and Candida tropicalis
ABSTRACT Candida albicans and Candida tropicalis are major hyphae-forming pathogens causing candidiasis. The rise of antifungal resistance underscores the need for new therapeutic strategies. Miltefosine (MFS), an alkylphosphocholine designated as an orphan drug for invasive candidiasis, has shown inhibitory, fungicida...