Review
Open access
Sep 2026
Complement system in kidney transplantation: from innate immune surveillance to a therapeutic and genetic engineering target
Kidney transplantation remains the most effective treatment for end-stage kidney disease; however, long-term graft survival is constrained by rejection and chronic graft injury, and donor shortages continue to drive interest in xenotransplantation. The complement system is increasingly recognized both as a terminal eff...
Y. Kakuta, Shuji Miyagawa, Shunsuke Mori et al.
· Frontiers in Immunology · 0 citations