Jul 2026
Stk11 loss in lung adenocarcinoma increases tumor CXCL16 and is associated with an expansion of Areg+ CXCR6+ IL-17-producing γδ T cells 2310280
Tumor Immunology: Cellular Responses and Tumor Microevironment (TIME) shows that tumor-intrinsic Stk11 loss in lung adenocarcinoma is associated with an expansion of lung gdT17 cells and supports a model in which these pro-tumor cells are recruited to the KS mouse lung via a CXCL16-CXCR6 axis.
Katherine J Horrigan, Joshua M. Ragusa, Somen K. Mistri et al.
· Journal of Immunology · 0 citations