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Song-Bai Liu

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Open access Sep 2026

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

It is demonstrated that IDH3A is significantly overexpressed in melanoma, primarily due to DNA copy number amplification, and a noncanonical role of IDH3A is uncovered as a nuclear regulator of transcription via YBX1, offering novel insight into metabolic enzyme reprogramming in melanoma.

Juan Ran, Yan-Chun Fang, Sheng-Ming Ruan et al. · 0 citations
Review Open access Aug 2026

EIF4EBP1 in Breast Cancer: Translational Control, Regulatory Networks, and Therapeutic Frontiers.

Eukaryotic initiation factor 4E-binding protein 1 (EIF4EBP1/4E-BP1) is a pivotal translational regulator with context-dependent roles in breast cancer pathogenesis. Its phosphorylation status, dynamically controlled by mammalian target of rapamycin (mTOR), mitogen-activated protein kinase (MAPK)/extracellular signal-re...

Wei-Jia Liu, Li-Li Hou, Dan-Dan Tang et al. · 0 citations

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