Exploring the Remodeling of the Microglial Communication Network and the Role of CADM1 in Vascular Dementia (VaD) Based on Single-Nucleus Transcriptomics.
INTRODUCTION Vascular dementia (VaD) is characterized by neurovascular unit dysfunction and neuroinflammation. However, the molecular regulators linking microglial activation to remodeling of intercellular communication remain incompletely understood. METHODS The human postmortem single-nucleus RNA-sequencing dataset...