Life is sustained by diverse far‐from‐equilibrium enzymatic reaction networks that reversibly sense and respond to environmental signals and precisely regulate biological functions. A key goal of chemistry is to develop enzymatic reaction networks (ERNs) with life‐like properties. Here we introduce an overview of the...
Zheng-Yang Dan, Ji-Chao Wang, Nina Lin et al.· ChemSystemsChem· 0 citations
A spatiotemporal sequential fluorescence-electrochemistry bimodal platform for both spatial mapping and precise quantitation of asparaginyl endopeptidase (AEP) activity in living single cells is developed and offers a powerful tool for studying enzyme heterogeneity, subcellular localization, and dynamic enzymatic activ...
This work engineer an exosomal nanoplatform, PpIX/siRNA@EXO-LOD, to simultaneously disrupt intra- and extracellular LA homeostasis, thereby enabling synergistic metabolic and photodynamic therapy (PDT) and demonstrates that this dual-regulation strategy effectively inhibits tumor growth, downregulates metastasis-relate...
Si-Si Zhou, Yu Cao, Xianbiao Wang et al.· Advanced Healthcare Material...· 0 citations
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