Author

Song Wu

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Oct 2026

MDK+ cancer-associated fibroblasts promote immunotherapy resistance through mitochondrial reprogramming in breast cancer.

Immunotherapy has improved outcomes for patients with breast cancer, yet therapeutic resistance remains a major clinical challenge. Therefore, we integrated single-cell and spatial transcriptomic data from breast cancer cohorts treated with immune checkpoint inhibitors to identify resistance-associated cellular populat...

Wei Deng, Yi-Dan Fan, Han-Qi Zhang et al. · Cancer Letters · 0 citations

Review Open access Jul 2026

Precision targeted therapy and immunotherapy in breast cancer: Advances and clinical frontiers.

An overview of current progress in targeted therapies and immunotherapy for breast cancer, highlighting their mechanisms, clinical utility, and challenges is provided.

Song Wu, Pangzhou Chen, Wen Zhou et al. · Chinese Medical Journal · 0 citations

Open access Jul 2026

Single-cell sequencing profiling of intratumoral heterogeneity and immunosuppressive microenvironment in primary thyroid cancer and lymph node metastases

This study comprehensively maps the coevolution of malignant thyrocyte plasticity and the immunosuppressive metastatic niche in thyroid cancer and provides a robust molecular rationale for developing next-generation immunotherapeutic strategies tailored to thyroid cancer.

Shu-hang Xu, Yaorong Su, Senmin Zhang et al. · Oncoimmunology · 0 citations