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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Sonia Di Bari

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Open access Aug 2026

Pan-CDK and PLK1 inhibitors as a novel approach for targeted treatment of adrenocortical carcinomas.

Adrenocortical carcinomas (ACC) are aggressive cancers with limited therapeutic options. Cyclin-dependent kinases (CDKs) 1/2/4 and polo-like kinase 1 (PLK1) are upregulated in ACC, suggesting their role as potential targets. This study investigated the anti-tumour efficacy of the pan-CDK inhibitors (CDKi) dinaciclib, A...

E. Esposito, E. Nozza, A. Barbieri et al. · 0 citations

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