Pan-cancer analysis of SPINT2 reveals context-dependent patterns and prognostic relevance across solid cancers
Serine Protease Inhibitor Kunitz type-2 (SPINT2) has been reported to play a role in the progression of various tumor types. This inhibitor is generally described as a tumor suppressor that affects migration and invasion. However, a few recent studies have reported the opposite, suggesting an oncogenic role for SP...