Author

Sonja Billerbeck

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Open access Sep 2026

The transcription factor Ste12(1) from Nakaseomyces glabratus acts pheromone-responsive in S. cerevisiae but seems decoupled from its cognate upstream GPCR in its native host

G-protein-coupled receptor (GPCR)-mediated signalling pathways govern critical cellular responses in fungi, including mating, biofilm formation, and virulence. The mating pathway of Saccharomyces cerevisiae, in which peptide-sensing GPCRs (peptide GPCRs) activate a MAP kinase cascade and the transcription factor Ste12,...

Min Lu, T. de Vroet, Sonja Billerbeck · bioRxiv · 0 citations

Open access Sep 2026

Unveiling the molecular architecture of Candida auris ribosome.

Using in-house rRNA sequencing, it is found that C. auris rRNA displays substantial divergence, including the lowest 18S rRNA identity among the pathogenic Candida species examined and an unusual substitution at a functionally important nucleotide in helix h31 of the small subunit P-site region.

A. Atamas, A. Stetsenko, D. Incarnato et al. · Structure · 0 citations