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Author

Sonja M. Best

2 papers indexed here

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Oct 2026

Viral deISGylation holds the key to the metabolic kingdom.

The interferon-induced modification of cellular and viral proteins by ISG15 inhibits viral infection and is reversed by virus-encoded deISGylases, but the broad physiological impacts of this host-pathogen clash remain unclear. In this issue of Immunity, Zhu et al. reveal that ISG15 modification broadly restricts key me...

Byron Shue, Sonja M. Best · 0 citations
Open access Sep 2026

Epigenetic regulation of DPP4 receptor expression by NONO enables replication of MERS-CoV

Middle East respiratory syndrome coronavirus (MERS-CoV), first reported in 2012, belongs to the Betacoronavirus genus, including SARS-CoV and SARS-CoV-2. Human-to-human transmission of MERS-CoV appears inefficient, but repeated spillover events have been reported from at least 27 countries, raising concern for future e...

Adam Hage, Mikhaila Janes, Seth D. Scott et al. · 0 citations

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