Open access
Sep 2026
Co-exposure to high temperature and mono(2-ethylhexyl) phthalate inhibits mouse antral follicle growth and estradiol synthesis: phthalate-heat interactions in the ovary
Abstract Humans are ubiquitously exposed to di(2-ethylhexyl) phthalate (DEHP), which is a phthalate plasticizer used in consumer goods that has been identified as a reproductive toxicant. DEHP toxicity is mediated by mono(2-ethylhexyl) phthalate (MEHP), its bioactive metabolite that has been shown to target ovarian pro...
Sundus Ghuneim, M. Wilson, Caroline Harper et al.
· Toxicological Sciences · 0 citations