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Author

Sophie Crux

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Open access Aug 2026

CX3CR1 Modulates Migration of Resident Microglia Towards Cortical Laser‐Induced Lesions

Microglia are innate immune cells of the central nervous system (CNS). They extend their processes and migrate toward injuries in vivo. However, how the fractalkine receptor (CX3CR1) influences microglial migration remains unknown. Label‐free proteomic profiling predicted changes in Ras homology family (RHO)‐signaling...

Jens Wagner, Henrike Antony, C. Hoyer et al. · 0 citations
Open access Aug 2026

Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence

DAXX, a histone chaperone and RTE repressor, is downregulated during aging, preserves microglia homeostasis and inhibits cellular senescence, highlighting the importance of heterochromatin maintenance in preserving adult microglial identity and plasticity, with broader implications for brain homeostasis, healthy aging...

Xin Yan, Christina Georgopoulou, Hang-Mao Lee et al. · 1 citation
Open access Jul 2026

CellColoc: A modular, open-source workflow for cell colocalization, segmentation, and feature extraction in microscopy images

By separating reusable analysis logic from project-specific configuration, CellColoc offers an extensible foundation for community-driven microscopy workflows that need transparent per-cell overlap classification, morphology readouts, and reusable batch analysis.

F. Musacchio, Henrike Antony, Arush Baijal et al. · 1 citation

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