Author

Soraya Alfonsin

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Review Open access Sep 2026

Resting-state functional and spectral alterations underlying cognitive decline in biomarker-confirmed Alzheimer's disease: A systematic review.

Alzheimer's disease (AD) is characterized by progressive cognitive decline associated with synaptic and large-scale network dysfunction. Resting-state alterations may provide functional correlates of AD pathology, but associations among intrinsic brain activity, biomarkers, and domain-specific cognition have not been s...

Soraya Alfonsín, Brenda Chino, J. de Frutos-Lucas et al. · NeuroImage: Clinical · 0 citations

Open access Aug 2026

Cognitive components derived from traditional neuropsychological tests and their associations with plasma p-tau217 and p-tau181 in mild cognitive impairment: a multisite analysis.

BACKGROUND Currently, no single biomarker can reliably identify preclinical Alzheimer's disease (AD), particularly at or before the mild cognitive impairment (MCI) stage. Given the heterogeneity of MCI, integrative approaches are needed to improve early risk stratification. OBJECTIVES (i) To derive robust latent cogn...

Ana S. Perez, Hugo L. Hammer, V. Andersson et al. · GeroScience · 0 citations