Ellagic Acid Attenuates High-Fat, High-Sucrose Diet-Induced Cardiac Fibrosis by Suppressing AGE–RAGE Signaling, Oxidative Stress, and Inflammation
A high-fat, high-sucrose (HFHS) diet promotes insulin resistance and accelerates cardiac fibrosis (CF) through advanced glycation end products (AGEs), oxidative stress, and inflammation. Ellagic acid (EA) possesses antioxidant, anti-inflammatory, and anti-glycation properties; however, its protective effects against CF...