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Author

Souren Sadhukhan

2 papers indexed here

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Open access Sep 2026

Phosphorylation-dependent control of transcription factor activity regulates temporal patterning of cortical cell fate specification

The development of the cerebral cortex requires precise temporal control of transcription factor (TF) activity to coordinate neuronal and glial lineage transitions. However, the molecular mechanisms coupling signaling dynamics to TF function remain unclear. Here, we combine proteomic, phosphoproteomic, and multi-omic...

Arun Mahesh, Anuj Kumar Dwivedi, Xuan Wang et al. · 0 citations
Open access Sep 2026

Uncovering pan-cancer signatures of chemoresistance

Chemotherapy resistance remains a formidable challenge in cancer treatment, driving high mortality rates worldwide. Despite significant advancements, it remains unclear whether conserved molecular programs underpin therapy resistance across cancer types. Here, we integrate single-cell RNA sequencing, spatial transcript...

Mohammed M. A. Inayatullah, Engin Demirdizen, Z. Keepers et al. · 0 citations

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