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Sowmya Soman

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Open access Sep 2026

Revealing RELL1 signaling relying on the phosphoregulatory network analysis

Introduction RELL1 (Receptor Expressed in Lymphoid Tissues-Like 1) is a member of the TNF receptor superfamily. Although the physiological ligands and mechanistic insights into cell signaling still remain to be elucidated, its over-expression is associated with poor prognosis and enhanced immune cell infiltration in ca...

Pathiyil Sajini Sekhar, Diya Sanjeev, Amal Fahma et al. · 0 citations
Aug 2026

Phosphosite-Centric Association of MBD3 and NuRD Complex Based on Meta-Analysis of Global Human Phosphoproteome.

Methyl-CpG-binding domain protein 3 (MBD3) is a member of the methyl-CpG-binding domain (MBD) family, which functions as a scaffold within the nucleosome remodeling and histone deacetylase complex (NuRD). MBD3 has been studied extensively in pluripotency and gene regulation, particularly through chromatin remodeling. E...

Rachael Dsouza, Vaishnavi Gopalakrishnan, Leona Dcunha et al. · 0 citations
Open access Jan 2026

Illuminating the Co‐Phosphoregulatory Network of the Dark Kinase STK10 by Omics Approaches

Serine/threonine‐protein kinase 10 (STK10), an ERM protein kinase, functions as a membrane–cytoskeleton linker and regulates lymphocyte cortical rigidity, cell shape, adhesion, and migration. Despite its emerging relevance in immune regulation and cancer, the phosphoregulatory mechanisms governing STK10 remain poorly u...

Vaishnavi Gopalakrishnan, Amal Fahma, Althaf Mahin et al. · 0 citations
Review Open access Aug 2026

Current insights into PHF14: molecular features and functional roles

Current knowledge on PHF14 structure, interaction partners, molecular functions, associated signaling pathways, and roles in diseases are summarized.

Vaishnavi Gopalakrishnan, Amal Fahma, Rajesh Raju et al. · 0 citations

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