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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Srikanth Karnati

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Open access Aug 2026

SPRTN preserves RNA polymerase I transcription under genotoxic drug stress in lung adenocarcinoma

Background Hyperactivated RNA polymerase I (Pol I)-driven ribosomal DNA (rDNA) transcription sustains malignant growth and chemotherapy tolerance in lung adenocarcinoma (LUAD). Genotoxic chemotherapeutics such as doxorubicin and cisplatin preferentially damage rDNA by inducing DNA-protein crosslinks (DPCs), yet how tum...

Mansi Sharma, Srikanth Karnati, S. Ergün et al. · 0 citations

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