Exploration of novel indolo[2,3-b]quinoxaline hybrids as InhA inhibitors: A multi-disciplinary approach involving synthesis, antimycobacterial evaluation and computational studies.
A library of 52 indolo[2,3-b]quinoxaline derivatives was designed and synthesized using a pharmacophore-hybridization strategy and subjected to comprehensive biological and computational evaluation, highlighting indolo[2,3-b]quinoxaline as promising antitubercular scaffold for further development.