Review
Open access
Aug 2026
Optimization of Focused Ultrasound-Mediated Blood–Brain Barrier Opening for CNS Therapeutic Delivery: Mechanistic Insights, Technical Parameters, and Clinical Translation
BBB microdisruption, particularly through FUS with microbubbles, represents a transformative platform for central nervous system gene therapy, and continued research is needed to standardize treatment protocols, characterize long-term safety, and facilitate broader clinical translation.
M. Rashad, Agastya Mittal, Srivardhan Chirasani et al.
· Journal of Molecular Patholo... · 0 citations