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Author

Stefan Bauer

2 papers indexed here

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Sep 2026

Inositol hexakisphosphate is a Cofactor and Modulator of ADAR1 RNA Editing Activity.

Adenosine-to-inosine (A-to-I) RNA editing by ADAR1 is a key post-transcriptional modification, and mutations in ADAR1 lead to Aicardi-Goutières syndrome (AGS), an autoimmune disorder. Despite its biological and clinical relevance, the regulation of ADAR1 activity remains incompletely understood. Using a combination of...

Francisco Antonio Venegas Solis, Mengsi Lu, Roni Cohen-Fultheim et al. · 0 citations
Open access Sep 2026

Cyclosporin A triggers a RIG-I-mediated interferon response through multiple cellular processes

The development of broad-spectrum antiviral agents is essential for preparedness against emerging viruses with pandemic potential. Cyclosporin A (CsA), a clinically approved immunosuppressant, has been shown to exert antiviral activity against a wide range of viruses. Recent evidence suggests that this effect is partia...

L. Meier, Martin Schauflinger, Pauline Neubecker et al. · 0 citations

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