Background Chronic obstructive pulmonary disease (COPD) is frequently associated with cardiovascular comorbidities. Obstructive sleep apnea (OSA) may coexist with COPD, forming the so‐called overlap syndrome (OS), and may further increase cardiovascular risk through intermittent hypoxia, systemic inflammation, and symp...
Ș. Oprea, Ștefan Dumitrache-Rujinski, C. Diaconu· Pulmonary Medicine· 0 citations
Pulmonary tuberculosis is one of the major public health issues globally. According to the World Health Organization, it is among the top 10 causes of death caused by a single pathogen. In Romania, its reported incidence rate in 2024 was approximately 60 per 100,000 people, making it the country with the highest in...
Alexandra-Maria Cristea, D. Zaharia, O. Parlițeanu et al.· Frontiers in Medicine· 0 citations
Background: Immunotherapy and targeted therapy have gained ground over conventional chemotherapy in treating various cancers. While pulmonary toxicity associated with these agents is rare, it represents a significant factor in both mortality and morbidity and may influence the overall success of cancer treatment. This...
C. Toma, Ș. Oprea, Ștefan Dumitrache-Rujinski et al.· Diseases· 0 citations
Long-term exposure to selected pollutants was associated with variations in PD-L1 expression and EGFR status, suggesting that environmental factors may contribute to tumor heterogeneity, but causal relationships cannot be established.
Denisa-Gabriela Ion-Andrei, Andre Barde, Cristina Cioti et al.· Biomedicines· 0 citations
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