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Stefania Maraka

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Review Open access Aug 2026

Cardiac Monitoring for Patients Undergoing Treatment With MEK Inhibitor Monotherapy

Aberrant activation of the RAS-RAF-MEK-ERK signaling pathway contributes to numerous malignancies, congenital syndromes, and cardiovascular disorders, establishing MEK inhibitors (MEKi) as crucial therapeutic agents. MEKi demonstrate substantial clinical benefit as monotherapy (e.g., NF1-associated tumors) or combinati...

J. Menteer, Devorah Segal, Stefania Maraka et al. · 0 citations

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