This review examines the analytical strategies used to detect and quantify circRNAs, including amplification-based methods (RT-qPCR, droplet digital PCR, and isothermal amplification), hybridization-based assays, sequencing approaches (short- and long-read RNA-seq), and emerging biosensor technologies.
A. Glovi, P. M. Kalligosfyri, A. Miglione et al.· iScience· 0 citations
This review provides a comprehensive overview of the key analytes employed in liquid biopsy, including circulating tumor DNA, circulating tumor cells, microRNAs, extracellular vesicles, and protein biomarkers with particular emphasis on their translational relevance in breast cancer.
Pritam Saha Podder, Debasree Bhadra, Canio Martinelli et al.· Exploration of Targeted Anti...· 0 citations
By bridging circRNA biology with advanced biosensor design, this work aims to accelerate translational research and guide the development of next-generation diagnostics for early disease detection, supporting a shift from reactive treatment to proactive health care.
A. Glovi, P. M. Kalligosfyri, A. Miglione et al.· Analytical Chemistry· 0 citations
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