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Author

Steffen Löck

2 papers indexed here

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Open access Oct 2026

Increased number of chemotherapy cycles during radiochemotherapy improves overall survival without increasing toxicity in locally advanced non-small cell lung cancer patients.

PURPOSE Radiochemotherapy (RCHT) followed by immunotherapy is the standard of care for unresectable, locally advanced non-small cell lung cancer (LA-NSCLC) patients. However, the impact of chemotherapy cycles and consolidation durvalumab on overall survival and toxicity remains uncertain in a real-life cohort. METHOD...

A. Simbirova, Steffen Löck, S. Appold et al. · 0 citations
Open access Oct 2026

Clinical Utility of Broad-Panel Profiling in Non-Small Cell Lung Cancer: Pairwise Co-Mutational Gene Patterns and PD-L1 Associations Define Stage-Specific Prognosis

Objectives: Precision medicine has improved outcomes in advanced lung cancer, but its implementation remains limited. The prospective LANTERN project (NCT05802771) involves comprehensive clinical and multi-omics data collection. Here, we report preliminary genomic findings, focusing on the prognostic impact of gene mut...

C. Sassorossi, E. De Paolis, Jessica Evangelista et al. · 0 citations

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